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Cyclin A (CCNA2) Blocking Peptide | CCNA2 blocking peptide

Cyclin A (CCNA2) Antibody (N-term) Blocking peptide

Gene Names
CCNA2; CCN1; CCNA
Synonyms
Cyclin A (CCNA2); Cyclin A (CCNA2) Antibody (N-term) Blocking peptide; Cyclin-A2; Cyclin-A; CCNA2; CCN1; CCNA; CCNA2 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human CCNA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
432
Cellular Location
Nucleus. Cytoplasm. Note: Cytoplasmic when associated with SCAPER
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CCNA2 blocking peptide
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
890
UniProt Accession #
Molecular Weight
48,551 Da
NCBI Official Full Name
Cyclin-A2
NCBI Official Synonym Full Names
cyclin A2
NCBI Official Symbol
CCNA2
NCBI Official Synonym Symbols
CCN1; CCNA
NCBI Protein Information
cyclin-A2
UniProt Protein Name
Cyclin-A2
Protein Family
UniProt Gene Name
CCNA2
UniProt Synonym Gene Names
CCN1; CCNA; Cyclin-A
UniProt Entry Name
CCNA2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008]

Uniprot Description

CCNA2: a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Protein type: Cell cycle regulation; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 4q27

Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: mitotic cell cycle G2/M transition DNA damage checkpoint; Ras protein signal transduction

Research Articles on CCNA2

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Product Notes

The CCNA2 ccna2 (Catalog #AAA9226759) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cyclin A (CCNA2), Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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