CRLS1 blocking peptide

CRLS1 Blocking Peptide (C-term)

Gene Names

CRLS1; CLS; CLS1; GCD10; C20orf155; dJ967N21.6

Synonyms

CRLS1; CRLS1 Blocking Peptide (C-term); Cardiolipin synthase; CLS; 278-; Protein GCD10 homolog; C20orf155; CLS1; CRLS1 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 213-226 of HUMAN CRLS1

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

202

Cellular Location

Mitochondrion inner membrane; Multi-pass membrane protein

Tissue Location

Highly expressed in tissues such as heart, skeletal muscle and liver.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for CRLS1 blocking peptide

Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.

NCBI and Uniprot Product Information

NCBI GI #

188536108

NCBI GeneID

54675

NCBI Accession #

NP_001120930.1

NCBI GenBank Nucleotide #

NM_001127458.1

UniProt Accession #

Q9UJA2; Q27RP0; Q69YQ5; D3DW09; E9PAT4

Molecular Weight

22,584 Da

NCBI Official Full Name

cardiolipin synthase (CMP-forming) isoform 2

NCBI Official Synonym Full Names

cardiolipin synthase 1

NCBI Official Symbol

CRLS1

NCBI Official Synonym Symbols

CLS; CLS1; GCD10; C20orf155; dJ967N21.6

NCBI Protein Information

cardiolipin synthase (CMP-forming)

UniProt Protein Name

Cardiolipin synthase (CMP-forming)

UniProt Gene Name

CRLS1

UniProt Synonym Gene Names

C20orf155; CLS1; CLS

UniProt Entry Name

CRLS1_HUMAN

NCBI Description

This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016]

Uniprot Description

CRLS1: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass; Transferase; Lipid Metabolism - glycerophospholipid; EC 2.7.8.-

Chromosomal Location of Human Ortholog: 20p13-p12.3

Cellular Component: mitochondrial inner membrane; mitochondrion

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity; cardiolipin synthase activity; CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity

Biological Process: cardiolipin biosynthetic process

Research Articles on CRLS1

1. transgenic expression of cardiolipin synthase attenuated maladaptive cardiolipin remodeling and bioenergetic inefficiency in myocardium rendered diabetic by streptozotocin treatment.

Similar Products

CRLS1 ELISA Kit

Host: n/a

Reactivity: Human

Apps: n/a

Product Notes

The CRLS1 crls1 (Catalog #AAA9230891) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CRLS1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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CRLS1 blocking peptide