CAPRIN2 blocking peptide

CAPRIN2 Blocking Peptide

Cat. Num. AAA9621581

• Gene Names: CAPRIN2; EEG1; EEG-1; C1QDC1; RNG140
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: CAPRIN2; CAPRIN2 Blocking Peptide; C1q domain-containing protein 1; C1QDC1; CAPR2_HUMAN; Caprin family member 2; Caprin-2; caprin2; Cytoplasmic activation/proliferation-associated protein 2; EEG 1; EEG1; Gastric cancer multidrug resistance-associated protein; KIAA1873; Protein EEG-1; RNA granule protein 140; RNG140; CAPRIN2 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for CAPRIN2 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for CAPRIN2 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 109734804
• NCBI GeneID: 65981
• UniProt Accession #: Q6IMN6; Q149P6; Q149P7; Q6IMN5; Q7Z371; Q8TE70; Q8TE71; Q96RN6; Q9H667; Q9HAL4; E4NKG2
• NCBI Official Full Name: CAPRIN2 protein
• NCBI Official Synonym Full Names: caprin family member 2
• NCBI Official Symbol: CAPRIN2
• NCBI Official Synonym Symbols: EEG1; EEG-1; C1QDC1; RNG140
• NCBI Protein Information: caprin-2
• UniProt Protein Name: Caprin-2
• Protein Family: Caprin
• UniProt Gene Name: CAPRIN2
• UniProt Entry Name: CAPR2_HUMAN

NCBI Description

The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Uniprot Description

C1QDC1: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. Belongs to the caprin family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 12p11

Cellular Component: centrosome; cytoplasm; mitochondrion; nucleus; receptor complex

Molecular Function: protein binding; receptor binding; RNA binding

Biological Process: negative regulation of cell growth; negative regulation of translation; positive regulation of dendrite morphogenesis; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein binding; positive regulation of transcription from RNA polymerase II promoter