C1RL blocking peptide
C1RL Antibody (Center) Blocking Peptide
Gene Names
C1RL; C1RL1; C1RLP; CLSPa; C1r-LP
Synonyms
C1RL; C1RL Antibody (Center) Blocking Peptide; Complement C1r subcomponent-like protein; C1r-LP; C1r-like protein; 3421-; C1r-like serine protease analog protein; CLSPa; C1RL1; C1RLP; CLSPA; C1RL blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
487
Cellular Location
Secreted.
Tissue Location
Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV- 3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for C1RL blocking peptide
Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,498 Da
NCBI Official Full Name
complement C1r subcomponent-like protein isoform 1
NCBI Official Synonym Full Names
complement C1r subcomponent like
NCBI Official Symbol
C1RL
NCBI Official Synonym Symbols
C1RL1; C1RLP; CLSPa; C1r-LP
NCBI Protein Information
complement C1r subcomponent-like protein
UniProt Protein Name
Complement C1r subcomponent-like protein
Protein Family
UniProt Gene Name
C1RL
UniProt Synonym Gene Names
C1RL1; C1RLP; CLSPA; C1r-LP; C1r-like protein; CLSPa
UniProt Entry Name
C1RL_HUMAN
Uniprot Description
C1RL: Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. Belongs to the peptidase S1 family.
Protein type: Protease; Secreted; EC 3.4.21.-; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component: extracellular space
Research Articles on C1RL
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Product Notes
The C1RL c1rl (Catalog #AAA9221505) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "C1RL, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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