Annexin A9 Blocking Peptide | ANXA9 blocking peptide
Annexin A9 Antibody Antigenic Blocking Peptide
Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.
NCBI and Uniprot Product Information
NCBI Description
The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]
Uniprot Description
ANXA9: a calcium/phospholipid-binding protein that may act as a low affinity receptor for acetylcholine. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Lipid-binding; Calcium-binding
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: cell surface; cytosol
Molecular Function: acetylcholine receptor activity; calcium ion binding; calcium-dependent phospholipid binding; phosphatidylserine binding; phospholipid binding; protein binding; protein homodimerization activity
Biological Process: cell-cell adhesion; signal transduction; synaptic transmission
Research Articles on ANXA9
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Product Notes
The ANXA9 anxa9 (Catalog #AAA542364) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Annexin A9 can be used in a range of immunoassay formats including, but not limited to, Immmunodepletion, Competition Assay. Western Blot: 1:500. Researchers should empirically determine the suitability of the ANXA9 anxa9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Annexin A9, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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