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Structure

Triclabendazole Biochemical

Triclabendazole

Purity
>=98%
Synonyms
Triclabendazole; Fasinex; 6-chloro-5-(2; 3-dichlorophenoxy)-2-methylsulfanyl-1H-benzimidazole; 5-Chloro-6-(2; 3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole; Triclabendazole biochemical
Ordering
For Research Use Only!
Specificity
A benzimidazole anthelminthic drug that binds to tubulin
Purity/Purification
>=98%
Form/Format
White to Off-White Powder
Solubilities
~3.6mg/ml in DMSO
Molecular Formula
C??H?Cl?N?OS
InChi
InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H; 1H3; (H; 18; 19)
InChi Key
NQPDXQQQCQDHHW-UHFFFAOYSA-N
SMILES
CSC1=NC2=CC(=C(C=C2N1)Cl)OC3=C(C(=CC=C3)Cl)Cl
CAS Number
68786-66-3
MDL Number
MFCD00864519
PubChem CID
50248
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Structure

Structure
Related Product Information for Triclabendazole biochemical
Triclabendazole is a benzimidazole anthelminthic drug that binds to tubulin. TCBZ is used to treat liver fluke (Fasciola hepatica) infections in cattle and humans. It is effective against fascioliasis in sheep at a dose of 10mg/body weight. Triclabendazole (5uM) protects yeast cells from death induced by alpha-synuclein, oxidants and heat stress. It decreases the intracellular level of cyclic AMP and triggers the translocation of the stress-resistance transcription factor Msn2 from the cytosol into the nucleus in yeast cells.
References
https://pubchem.ncbi.nlm.nih.gov/compound/50248

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Product Notes

The Triclabendazole (Catalog #AAA8400478) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Triclabendazole, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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