Structure
Tranilast Biochemical
Tranilast
Purity
>98% (HPLC)
Synonyms
Tranilast; MK-341; SB-252218; Tranilast biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 32.7mg/mL (100mM) (<1mg/mL refers to the product slightly soluble or insoluble)
Target
Other Targets
Receptor
Others
Chemical Name
Benzoic acid, 2-[[3-(3, 4-dimethoxyphenyl)-1-oxo-2-propenyl]amino]-(9CI)
SMILES
COC1=C(C=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O)OC
Molecular Formula
C18H17NO5
CAS Number
53902-12-8
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Tranilast biochemical
A compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-beta1-induced proliferation and migration of vascular medial smooth muscle cells; inhibits endotoxin-induced PGE2 (IC50=1-20uM), thromboxane B2 (IC50= 10-50uM), TGF-beta1 (IC50=100-200uM), and IL-8 (IC50=100uM) formation, but has no effect on TNF-alpha; also inhibits VEGF-induced angiogenetic activities. Allergy Approved
Product Categories/Family for Tranilast biochemical
References
1. Capper EA, et al. J Pharmacol Exp Ther. 2000 Dec; 295 (3):1061-9.
2. Ikai K, et al. Biochem Pharmacol. 1989 Aug 15; 38 (16):2673-6.
3. Koyama S, et al. Br J Pharmacol. 1999 May; 127 (2):537-45.
2. Ikai K, et al. Biochem Pharmacol. 1989 Aug 15; 38 (16):2673-6.
3. Koyama S, et al. Br J Pharmacol. 1999 May; 127 (2):537-45.
Similar Products
Product Notes
The Tranilast (Catalog #AAA3604922) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tranilast, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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