Structure
Tenovin-6 Biochemical
Tenovin-6
Purity
>=95%
Synonyms
Tenovin-6; 4-tert-butyl-N-[[4-[5- (dimethylamino) pentanoylamino]phenyl]carbamothioyl]benzamide; 4-tert-butyl-N- (4- (5- (dimethylamino) pentanamido) phenylcarbamothioyl) benzamide; Benzamide; N-[[[4-[[5- (dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4- (1; 1-dimethylethyl)-; Tenovin-6 biochemical
Purity/Purification
>=95%
Form/Format
Crystalline solid
Solubility
~20 mg/ml in DMSO
~1mg/ml in Ethanol
~1mg/ml in Ethanol
Molecular Formula
C??H??N?O?S
CAS Number
1011557-82-6
MDL Number
MFCD11976906
PubChem CID
24772043
SMILES
CC (C)(C)C1=CC=C (C=C1)C (=O)NC (=S)NC2=CC=C (C=C2)NC (=O)CCCCN (C)C
InChi
InChI=1S/C25H34N4O2S/c1-25 (2,3)19-11-9-18 (10-12-19)23 (31)28-24 (32)27-21-15-13-20 (14-16-21)26-22 (30)8-6-7-17-29 (4)5/h9-16H,6-8,17H2,1-5H3, (H,26,30)(H2,27,28,31,32)
InChi Key
BVJSXSQRIUSRCO-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for Tenovin-6 biochemical
Tenovin-6 is a SirT2 inhibitor and a p53 activator. It is a water-soluble analog of Tenovin-1. Tenovins inhibit the protein-deacetylase activities of SirT1 and SirT2. The IC50 for inhibiting human SirT1 and SirT2 peptide deacetylase activity is 21 uM and 10 uM respectively. Tenovin-6 potently inhibits the proliferation of diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia cells.
Product Categories/Family for Tenovin-6 biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/24772043
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Product Notes
The Tenovin-6 (Catalog #AAA848953) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tenovin-6, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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