Structure
CAY10602 Biochemical
CAY10602
Purity
>=95%
Synonyms
CAY10602; 3- (benzenesulfonyl)-1- (4-fluorophenyl) pyrrolo[3; 2-b]quinoxalin-2-amine; 1- (4-Fluorophenyl)-3- (phenylsulfonyl)-1H-pyrrolo (2; 3-B) quinoxalin-2-amine; SIRT1 Activator II; CAY10602 biochemical
Purity/Purification
>=95%
Form/Format
A crystalline solid
Solubility
~20 mg/ml in DMSO and DMF
Molecular Formula
C??H??FN?O?S
CAS Number
374922-43-7
MDL Number
MFCD02236691
PubChem CID
1915791
SMILES
C1=CC=C (C=C1)S (=O)(=O)C2=C (N (C3=NC4=CC=CC=C4N=C23)C5=CC=C (C=C5)F)N
InChi
InChI=1S/C22H15FN4O2S/c23-14-10-12-15 (13-11-14)27-21 (24)20 (30 (28,29)16-6-2-1-3-7-16)19-22 (27)26-18-9-5-4-8-17 (18)25-19/h1-13H,24H2
InChi Key
CSFVFDHRYKBBPD-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for CAY10602 biochemical
CAY10602 is an activator of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. SIRT1 alters gene expression by deacetylating transcription factors such as NF-kappaB, p53, and FOXO. CAY10602 suppresses the NF-kappaB-dependent induction of TNF-alpha by lipopolysaccharide in THP-1 cells at 20 uM and 60 uM. It is more potent as a suppressor of TNF-alpha release than resveratrol.
Product Categories/Family for CAY10602 biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/1915791
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Product Notes
The CAY10602 (Catalog #AAA849009) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CAY10602, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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