Structure
SUVN-G3031 dihydrochloride Biochemical
SUVN-G3031 dihydrochloride
Purity
>98% (HPLC)
Synonyms
SUVN-G3031 dihydrochloride; SUVN-G 3031; SUVN-G3031 dihydrochloride biochemical
Purity/Purification
>98% (HPLC)
Target
Histamine Receptor
Receptor
Histamine Receptor
Chemical Name
N-[4-(l-Cyclobutylpiperidin-4-yloxy) phenyl]-2-(morpholin-4-yl) acetamide dihydrochloride
SMILES
C1CC(C1)N2CCC(CC2)OC3=CC=C(C=C3)NC(=O)CN4CCOCC4.Cl.Cl
Molecular Formula
C21H33Cl2N3O3
CAS Number
1394808-20-8
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for SUVN-G3031 dihydrochloride biochemical
SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73nM (hH3R); exhibited an IC50 of 20nM with progressive inhibition of (R)-alpha-methylhistamine (0.03uM) induced agonist activity in [35S]-GTPgammaS binding assay using CHO-K1 cells expressing human H3R membranes; reverses (R)-alpha-methylhistamine induced dipsogenia in vivo. Parkinson Disease Phase 1 Clinical
Product Categories/Family for SUVN-G3031 dihydrochloride biochemical
References
1. Nirogi R, et al. J Med Chem. 2019 Jan 10. doi: 10.1021/acs.jmedchem.8b01280.
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Product Notes
The SUVN-G3031 dihydrochloride (Catalog #AAA3601646) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SUVN-G3031 dihydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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