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Structure

SRT 3025 Biochemical

SRT 3025

Purity
>98% (HPLC)
Synonyms
SRT 3025; SRT3025; SRT 3025 biochemical
Ordering
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=32mg/mL (52.79mM)
Target
Sirtuin
Receptor
Sirtuin
Chemical Name
5-(3-methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5, 4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride
SMILES
COCCCC1=C(N=C(S1)C2=CC=CC=C2)C(=O)NC3=CC=CC=C3C4=NC5=C(S4)N=CC(=C5)CN6CCCC6.Cl
Molecular Formula
C31H32ClN5O2S2
CAS Number
2070015-26-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for SRT 3025 biochemical
SRT3025 is a potent, orallu actuve SIRT1 activator that activates wild-type Sirt1 protein, but not the Sirt1 mutant E230K; increases deacetylation of hepatic p65 and skeletal muscle Foxo1 and decreases plasma levels of LDL-cholesterol and total cholesterol and reduced atherosclerosis in vivo. Diabetes Phase 1 Clinical
Product Categories/Family for SRT 3025 biochemical
References
1. Miranda MX, et al. Eur Heart J. 2015 Jan 1; 36 (1):51-9.
2. Chini CC, et al. Clin Cancer Res. 2016 May 15; 22 (10):2496-507.
3. Artsi H, et al. Endocrinology. 2014 Sep; 155 (9):3508-15.L7948:M+M7950

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Product Notes

The SRT 3025 (Catalog #AAA3603223) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SRT 3025, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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