O-Benzoyl-(S)-(-)-Blebbistatin Biochemical
O-Benzoyl-(S)-(-)-Blebbistatin
Synonyms
O-Benzoyl-(S)-(-)-Blebbistatin; O-Benzoyl-(S)-(-)-Blebbistatin biochemical
Molecular Formula
C25H20N2O3
Melting Point
147-148 degree C
Solubility
Chloroform, Dichloromethane, DMSO, Ethyl Acetate, Methanol
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for O-Benzoyl-(S)-(-)-Blebbistatin biochemical
A derivative of Blebbistatin, a compound that blockes myosin II-dependent cell processes.
As part of a defined medium for growth of human Pluripotent stem (hPS) cells, Blebbistatin acts as an inhibitor of nonmuscle myosin II (NMII) and enhances the survival of hPS cells.
Preventing cell death of Human pluripotent stem (hPS) cells, such as human embryonic stem (hES) and induced pluripotent stem (hiPS) cells, has been a stumbling block to avenues of investigation of with these cell types. The most current culture methods for growing hPS cells require animal-derived materials like Matrigel, for coating the culture surfaces, without which hPS cells cannot adhere to the culture plate. The drawback in using these feeder cells is they can potentially contaminate hPS cells by introducing viruses and other unknown pathogens.
The active enantiomer of Blebbistatin (so named because of its ability to block cell blebbing) is the (S)-(-)-Blebbistatin form. MyBioSource offers the racemic mixture of Blebbistatin, along with the active (S)-(-) form and the inactive (R)-(+) form (which can be used as a negative control).
As part of a defined medium for growth of human Pluripotent stem (hPS) cells, Blebbistatin acts as an inhibitor of nonmuscle myosin II (NMII) and enhances the survival of hPS cells.
Preventing cell death of Human pluripotent stem (hPS) cells, such as human embryonic stem (hES) and induced pluripotent stem (hiPS) cells, has been a stumbling block to avenues of investigation of with these cell types. The most current culture methods for growing hPS cells require animal-derived materials like Matrigel, for coating the culture surfaces, without which hPS cells cannot adhere to the culture plate. The drawback in using these feeder cells is they can potentially contaminate hPS cells by introducing viruses and other unknown pathogens.
The active enantiomer of Blebbistatin (so named because of its ability to block cell blebbing) is the (S)-(-)-Blebbistatin form. MyBioSource offers the racemic mixture of Blebbistatin, along with the active (S)-(-) form and the inactive (R)-(+) form (which can be used as a negative control).
Product Categories/Family for O-Benzoyl-(S)-(-)-Blebbistatin biochemical
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Product Notes
The O-Benzoyl-(S)-(-)-Blebbistatin (Catalog #AAA6014638) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "O-Benzoyl-(S)-(-)-Blebbistatin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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