Structure
Eliprodil Biochemical
Eliprodil
Purity
>98% (HPLC)
Synonyms
Eliprodil; SL-820715; Eliprodil biochemical
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
iGluR
Receptor
NR2B-NMDA
Chemical Name
1-Piperidineethanol, alpha-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]
SMILES
OC(C1=CC=C(Cl)C=C1)CN2CCC(CC3=CC=C(F)C=C3)CC2
Molecular Formula
C20H23ClFNO
CAS Number
119431-25-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Eliprodil biochemical
Eliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100uM); inhibits [3H]norepinephrine release from cortical and hippocampal slices but enhances the basal efflux of endogenous and tritiated dopamine from striatal slices, also blocks the uptake of [3H]dopamine into striatal synaptosomes with IC50 of 1.5uM; reduces the volume of infarction in models of focal cerebral ischemia. Stroke Phase 3 Discontinued
Product Categories/Family for Eliprodil biochemical
References
1. Woodward JJ, et al. Eur J Pharmacol. 1992 Jan 21; 210 (3):265-70.
2. Carter CJ, et al. J Pharmacol Exp Ther. 1990 May; 253 (2):475-82.
3. Carter C, et al. Eur J Pharmacol. 1989 May 30; 164 (3):611-2.
4. Bath CP, et al. Eur J Pharmacol. 1996 Mar 28; 299 (1-3):103-12.
2. Carter CJ, et al. J Pharmacol Exp Ther. 1990 May; 253 (2):475-82.
3. Carter C, et al. Eur J Pharmacol. 1989 May 30; 164 (3):611-2.
4. Bath CP, et al. Eur J Pharmacol. 1996 Mar 28; 299 (1-3):103-12.
Similar Products
Product Notes
The Eliprodil (Catalog #AAA3600679) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Eliprodil, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
