Structure
CH7057288 Biochemical
CH7057288
Purity
>=98% by HPLC
Synonyms
CH7057288; CH-7057288; N- (tert-butyl)-2- ( (6; 6-dimethyl-8- (methylsulfonamido)-11-oxo-6; 11-dihydronaphtho[2; 3-b]benzofuran-3-yl) ethynyl)-6-methylisonicotinamide; CH7057288 biochemical
Purity/Purification
>=98% by HPLC
Form/Format
Crystalline solid
Solubility
>30 mg/ml in DMSO
Molecular Formula
C??H??N?O?S
CAS Number
2095616-82-1
PubChem CID
131839646
SMILES
CC1=NC (=CC (=C1)C (=O)NC (C)(C)C)C#CC2=CC3=C (C=C2)C4=C (O3)C (C5=C (C4=O)C=CC (=C5)NS (=O)(=O)C)(C)C
InChi
InChI=1S/C32H31N3O5S/c1-18-14-20 (30 (37)34-31 (2,3)4)16-21 (33-18)10-8-19-9-12-24-26 (15-19)40-29-27 (24)28 (36)23-13-11-22 (35-41 (7,38)39)17-25 (23)32 (29,5)6/h9,11-17,35H,1-7H3, (H,34,37)
InChi Key
DCGOHGQJHJXBGW-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for CH7057288 biochemical
CH7057288 as a potent and selective TRK (tropomyosin receptor kinase) inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth. CH7057288 shows selective inhibitory activity against TRKA, TRKB, and TRKC in cell-free kinase assays and suppresses proliferation of TRK fusion-positive cell lines, but not that of TRK-negative cell lines.
Product Categories/Family for CH7057288 biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/131839646
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Product Notes
The CH7057288 (Catalog #AAA848788) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CH7057288, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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