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Western Blot (WB)

Rabbit anti-Mouse MART-1/Melan-A Polyclonal Antibody | anti-Melan-A antibody

Anti-MART-1/Melan-A Antibody

Gene Names
Mlana; Mart1; A930034P04Rik
Reactivity
Mouse
Applications
Western Blot
Purity
Affinity purified rabbit IgG
Synonyms
MART-1/Melan-A; Polyclonal Antibody; Anti-MART-1/Melan-A Antibody; Melanoma antigen recognized by T-cells 1; Antigen LB39-AA; Antigen SK29-AA; MART-1; Melan-A; anti-Melan-A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Polyclonal antibody to detect MART-1/Melan-A
Purity/Purification
Affinity purified rabbit IgG
Form/Format
Colorless liquid. In PBS pH7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.03% proclin
Applicable Applications for anti-Melan-A antibody
Western Blot (WB)
Application Notes
WB: 1-4ug
Immunogen
Recombinant mouse MART-1 protein
Positive Control
WB: Recombinant protein
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use
Shelf life: ~12 months

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-Melan-A antibody
MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.
Product Categories/Family for anti-Melan-A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17.6 kDa
NCBI Official Full Name
melanoma antigen recognized by T-cells 1
NCBI Official Synonym Full Names
melan-A
NCBI Official Symbol
Mlana
NCBI Official Synonym Symbols
Mart1; A930034P04Rik
NCBI Protein Information
melanoma antigen recognized by T-cells 1
UniProt Protein Name
Melan-A
UniProt Gene Name
Mlana
UniProt Entry Name
Q2TA50_MOUSE

Uniprot Description

MLANA: Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

Protein type: Cell surface; Membrane protein, integral

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; melanosome; trans-Golgi network

Research Articles on Melan-A

Similar Products

Product Notes

The Melan-A mlana (Catalog #AAA847217) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MART-1/Melan-An Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MART-1/Melan-A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1-4ug. Researchers should empirically determine the suitability of the Melan-A mlana for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MART-1/Melan-A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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