Structure
BGC20-1531 Biochemical
BGC20-1531
Purity
>98% (HPLC)
Synonyms
BGC20-1531; PGN-1531; AP 1531; BGC 20-1531; BGC20-1531 biochemical
Purity/Purification
>98% (HPLC)
Target
Prostaglandin Receptor
Receptor
Prostaglandin Receptor
Chemical Name
4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide hydrochloride
SMILES
CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(O2)C)COC3=CC=C(C=C3)C4=NC=C(C=C4)OC.Cl
Molecular Formula
C26H25ClN2O6S
CAS Number
1962928-26-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for BGC20-1531 biochemical
BGC20-1531 (PGN-1531, AP 1531) is a potent, selective prostanoid EP receptor EP antagonist, exhibits high affinity at recombinant human EP4 receptors expressed in cell lines (pKB=7.6) and native EP4 receptors in human cerebral and meningeal artery (pKB=7.6-7.8); shows no appreciable affinity at a wide range of other receptors (including other prostanoid receptors), channels, transporters and enzymes (pKi <5); competitively antagonizes PGE (2)-induced vasodilatation of human middle cerebral (pK (B) 7.8) and meningeal (pK (B) 7.6) arteries in vitro, and PGE (2)-induced increase in canine carotid blood flow in vivo. Migraine Phase 2 Discontinued
Product Categories/Family for BGC20-1531 biochemical
References
1. Maubach KA, et al. Br J Pharmacol. 2009 Jan; 156 (2):316-27.
2. Antonova M, et al. J Headache Pain. 2011 Oct; 12 (5):551-9.
2. Antonova M, et al. J Headache Pain. 2011 Oct; 12 (5):551-9.
Similar Products
Product Notes
The BGC20-1531 (Catalog #AAA3603079) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BGC20-1531, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
