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Structure

Adaphostin Biochemical

Adaphostin

Purity
>=98% by HPLC
Synonyms
Adaphostin; AG 957 Adamantyl Ester; NSC-680410; 4-[[(2; 5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13; 7]dec-1-yl ester; Adaphostin biochemical
Ordering
For Research Use Only!
Specificity
A p210bcr/abl kinase inhibitor
Purity/Purification
>=98% by HPLC
Form/Format
Off-white solid
Solubilities
>30mg/ml Ethanol; >30mg/ml DMSO
Molecular Formula
C??H??NO?
InChi
InChI=1S/C24H27NO4/c26-21-5-6-22(27)19(10-21)14-25-20-3-1-18(2-4-20)23(28)29-24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6; 10; 15-17; 25-27H; 7-9; 11-14H2
InChi Key
YJZSUCFGHXQWDM-UHFFFAOYSA-N
SMILES
C1C2CC3CC1CC(C2)(C3)OC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O
CAS Number
241127-58-2
MDL Number
MFCD06411386
PubChem CID
387042
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA

Structure

Structure
Related Product Information for Adaphostin biochemical
Adaphostin is a p210bcr/abl tyrosine kinase inhibitor (IC50 = 14uM) that displays anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 and other cancer cell lines. Adaphostin is a potent inducer of myeloid cell death.
References
https://pubchem.ncbi.nlm.nih.gov/compound/387042

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Product Notes

The Adaphostin (Catalog #AAA8400425) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Adaphostin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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