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Structure

4u8C Biochemical

4u8C

Purity
>=98% by HPLC
Synonyms
4u8C; IRE1 Inhibitor III; 7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde; 4u8C biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98% by HPLC
Form/Format
White to off-white solid
Solubility
>25 mg/ml in DMSO
Molecular Formula
C??H?O?
CAS Number
14003-96-4
PubChem CID
12934390
SMILES
CC1=CC (=O)OC2=C1C=CC (=C2C=O)O
InChi
InChI=1S/C11H8O4/c1-6-4-10 (14)15-11-7 (6)2-3-9 (13)8 (11)5-12/h2-5,13H,1H3
InChi Key
RTHHSXOVIJWFQP-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months

Structure

Structure
Related Product Information for 4u8C biochemical
4u8C is a selective inhibitor of IRE1alpha ribonuclease (RNase) activity (IC50 = 60 nM). It blocks substrate access to the active site of IRE1alpha and inactivates IRE1alpha-mediated mRNA degradation. Displays no effect on the IRE1alpha-related endoribonuclease RNase L.
References
https://pubchem.ncbi.nlm.nih.gov/compound/12934390

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Product Notes

The 4u8C (Catalog #AAA848769) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "4u8C, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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