Structure
N-Acetyl-4-benzoquinone Imine Biochemical
N-Acetyl-4-benzoquinone Imine
Purity
>=90% by HPLC
Synonyms
N-Acetyl-4-benzoquinone Imine; N- (4-oxo-2; 5-cyclohexadien-1-ylidene)-acetamide; NAPQI; N-Acetyl-4-benzoquinone Imine biochemical
Purity/Purification
>=90% by HPLC
Form/Format
Pale yellow to dark brown solid
Solubility
CHCl3 (1 mg/ml) or EtOAc (1 mg/ml)
Molecular Formula
C?H?NO?
CAS Number
50700-49-7
MDL Number
MFCD00078909
PubChem CID
39763
SMILES
CC (=O)N=C1C=CC (=O)C=C1
InChi
InChI=1S/C8H7NO2/c1-6 (10)9-7-2-4-8 (11)5-3-7/h2-5H,1H3
InChi Key
URNSECGXFRDEDC-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Protect from air and light
Shelf life: ~36 months
Structure
Structure
Related Product Information for N-Acetyl-4-benzoquinone Imine biochemical
N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic cytochrome P450 3A4 and 2E1 metabolite of Acetaminophen. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.
Product Categories/Family for N-Acetyl-4-benzoquinone Imine biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/39763
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Product Notes
The N-Acetyl-4-benzoquinone Imine (Catalog #AAA848583) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "N-Acetyl-4-benzoquinone Imine, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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