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Structure

10-Deacetylbaccatin III Biochemical

10-Deacetylbaccatin III

Purity
>=98%
Synonyms
10-Deacetylbaccatin III; (2aR; 4S; 4aS; 6R; 9S; 11S; 12S; 12aR; 12bS)-12b- (acetyloxy)-12- (benzoyloxy)-1; 2a; 3; 4; 4a; 6; 9; 10; 11; 12; 12a; 12b-dodecahydro-4; 11-tetrahydroxy-4a; 8; 13; 13-tetramethyl-7; 11-methano-5H-cyclodeca[3; 4]benz[1; 2-b]oxet-5-one; NSC 251677; NSC-251677; 10-Deacetylbaccatin III biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98%
Form/Format
White solid
Solubility
~20 mg/ml in DMSO
Molecular Formula
C??H??O??
CAS Number
32981-86-5
MDL Number
MFCD00132913
PubChem CID
154272
SMILES
O[C@H]1C[C@@] ([H])(OC2)[C@@]2 ([C@@] ([H])([C@H] (OC (C3=CC=CC=C3)=O)[C@@] (C[C@@H] (C (C)=C4[C@H]5O)O)(O)C4 (C)C)[C@]1 (C)C5=O)OC (C)=O
InChi
InChI=1S/C29H36O10/c1-14-17 (31)12-29 (36)24 (38-25 (35)16-9-7-6-8-10-16)22-27 (5,23 (34)21 (33)20 (14)26 (29,3)4)18 (32)11-19-28 (22,13-37-19)39-15 (2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1
InChi Key
YWLXLRUDGLRYDR-ZHPRIASZSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months

Structure

Structure
Related Product Information for 10-Deacetylbaccatin III biochemical
10-Deacetylbaccatin III is a precursor in the semisynthetic synthesis of paclitaxel; acts as an inhibitor of microtubule assembly (IC50s = 23 and 0.9 uM for porcine brain and Physaram microtubules, respectively). 10-Deacetylbaccatin III also selectively inhibits growth of L. donovani intracellular amastigotes within J774 murine macrophages (IC50 = 70 nM), while having no effect on macrophage morphology.
Product Categories/Family for 10-Deacetylbaccatin III biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/154272

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Product Notes

The 10-Deacetylbaccatin III (Catalog #AAA848927) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "10-Deacetylbaccatin III, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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