Structure
Cabazitaxel Biochemical
Cabazitaxel
Purity
>=98% by HPLC
Synonyms
Cabazitaxel; RPR116258A; (2aR; 4S; 4aS; 6R; 9S; 11S; 12S; 12aR; 12bS)-12b-acetoxy-9- ( ( (2R; 3S)-3- ( (tert-butoxycarbonyl) amino)-2-hydroxy-3-phenylpropanoyl) oxy)-11-hydroxy-4; 6-dimethoxy-4a; 8; 13; 13-tetramethyl-5-oxo-2a; 3; 4; 4a; 5; 6; 9; 10; 11; 12; 12a; 12b-dodecahydro-1H-7; 11-methanocyclodeca[3; 4]benzo[1; 2-b]oxet-12-yl benzoate.; XRP6258; TXD-258; Cabazitaxel biochemical
Purity/Purification
>=98% by HPLC
Form/Format
White solid
Solubility
>5 mg/ml DMSO
Molecular Formula
C??H??NO??
CAS Number
183133-96-2
MDL Number
MFCD18827611
PubChem CID
9854073
SMILES
CC1=C2C (C (=O)C3 (C (CC4C (C3C (C (C2 (C)C)(CC1OC (=O)C (C (C5=CC=CC=C5)NC (=O)OC (C)(C)C)O)O)OC (=O)C6=CC=CC=C6)(CO4)OC (=O)C)OC)C)OC
InChi
InChI=1S/C45H57NO14/c1-24-28 (57-39 (51)33 (48)32 (26-17-13-11-14-18-26)46-40 (52)60-41 (3,4)5)22-45 (53)37 (58-38 (50)27-19-15-12-16-20-27)35-43 (8,36 (49)34 (55-10)31 (24)42 (45,6)7)29 (54-9)21-30-44 (35,23-56-30)59-25 (2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3, (H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
InChi Key
BMQGVNUXMIRLCK-OAGWZNDDSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for Cabazitaxel biochemical
Cabazitaxel is a second generation semisynthetic taxane derived from 10-deacetylbaccatin with potent anticancer activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Cabazitaxel is more potent than docetaxel in P-glycoprotein-expressing cell lines with in vitro acquired resistance to taxanes or other chemotherapeutic agents.
Product Categories/Family for Cabazitaxel biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/9854073
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Product Notes
The Cabazitaxel (Catalog #AAA848675) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cabazitaxel, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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