BAG family molecular chaperone regulator 2 (Bag2) Recombinant Protein | Bag2 recombinant protein
Recombinant Mouse BAG family molecular chaperone regulator 2 (Bag2)
Gene Names
Bag2; BC016230; 2610042A13Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
BAG family molecular chaperone regulator 2 (Bag2); Recombinant Mouse BAG family molecular chaperone regulator 2 (Bag2); Bag2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-210. Full Length of Mature Protein
Sequence
AQAKISAKAHEGRFCRSSSMADRSSRLLESLDQLELRVEALRDAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQEESLKHATRIIDEVVSKFLDDLGNAKSHLMSLYSACSSEVPPGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIDNSDKAIKLLEHAKGAGSKSLQNTDGKFN
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Bag2 recombinant protein
BAG proteins compete with Hip for binding to the Hsc70
Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,474 Da
NCBI Official Full Name
BAG family molecular chaperone regulator 2
NCBI Official Synonym Full Names
BCL2-associated athanogene 2
NCBI Official Symbol
Bag2
NCBI Official Synonym Symbols
BC016230; 2610042A13Rik
NCBI Protein Information
BAG family molecular chaperone regulator 2
UniProt Protein Name
BAG family molecular chaperone regulator 2
Protein Family
UniProt Gene Name
Bag2
UniProt Synonym Gene Names
BAG-2
Uniprot Description
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release.
Research Articles on Bag2
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Product Notes
The Bag2 bag2 (Catalog #AAA1323686) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-210. Full Length of Mature Protein. The amino acid sequence is listed below: AQAKISAKAH EGRFCRSSSM ADRSSRLLES LDQLELRVEA LRDAATAVEQ EKEILLEMIH SIQNSQDMRQ ISDGEREELN LTANRLMGRT LTVEVSVETI RNPQQEESLK HATRIIDEVV SKFLDDLGNA KSHLMSLYSA CSSEVPPGPV DQKFQSIVIG CALEDQKKIK RRLETLLRNI DNSDKAIKLL EHAKGAGSKS LQNTDGKFN. It is sometimes possible for the material contained within the vial of "BAG family molecular chaperone regulator 2 (Bag2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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