Human ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D ELISA Kit | ATP6V1D elisa kit
Human V-type proton ATPase subunit D, ATP6V1D ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008]
Uniprot Description
ATP6V1D: Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase D subunit family.
Protein type: Energy Metabolism - oxidative phosphorylation; Hydrolase; EC 3.6.3.14
Chromosomal Location of Human Ortholog: 14q23-q24.2
Cellular Component: centrosome; membrane; lysosomal membrane; cytosol; cilium
Molecular Function: protein binding; ATPase activity, coupled to transmembrane movement of substances
Biological Process: interaction with host; proton transport; cellular iron ion homeostasis; insulin receptor signaling pathway; cilium biogenesis; transferrin transport; transmembrane transport
Research Articles on ATP6V1D
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Product Notes
The Human ATP6V1D atp6v1d (Catalog #AAA9338463) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338463 ELISA Kit recognizes Human ATP6V1D. It is sometimes possible for the material contained within the vial of "ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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