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Human PRA1 family protein 3 ELISA Kit | ARL6IP5 elisa kit

Human PRA1 family protein 3 (ARL6IP5) ELISA Kit

Gene Names
ARL6IP5; JWA; jmx; hp22; PRAF3; Yip6b; DERP11; HSPC127; addicsin; GTRAP3-18
Reactivity
Human
Synonyms
PRA1 family protein 3; Human PRA1 family protein 3 (ARL6IP5) ELISA Kit; ARL6IP5 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human ARL6IP5. No significant cross-reactivity or interference between Human ARL6IP5 and analogues was observed.
Sequence Length
188
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for ARL6IP5 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate ARL6IP5 in samples. An antibody specific for ARL6IP5 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyARL6IP5 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ARL6IP5 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ARL6IP5 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,615 Da
NCBI Official Full Name
PRA1 family protein 3
NCBI Official Synonym Full Names
ADP ribosylation factor like GTPase 6 interacting protein 5
NCBI Official Symbol
ARL6IP5
NCBI Official Synonym Symbols
JWA; jmx; hp22; PRAF3; Yip6b; DERP11; HSPC127; addicsin; GTRAP3-18
NCBI Protein Information
PRA1 family protein 3
UniProt Protein Name
PRA1 family protein 3
Protein Family
UniProt Gene Name
ARL6IP5
UniProt Synonym Gene Names
DERP11; JWA; PRA2; PRAF3; ARL-6-interacting protein 5; Aip-5

NCBI Description

Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. [provided by RefSeq, Jul 2008]

Uniprot Description

ARL6IP5: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. Belongs to the PRA1 family.

Protein type: Cytoskeletal; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3p14.1

Cellular Component: cytoskeleton; endoplasmic reticulum membrane; integral component of membrane; membrane; plasma membrane

Molecular Function: protein binding

Biological Process: induction of apoptosis by oxidative stress; L-glutamate transport; negative regulation of L-glutamate transport; positive regulation of apoptosis; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of stress-activated MAPK cascade

Research Articles on ARL6IP5

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Product Notes

The Human ARL6IP5 arl6ip5 (Catalog #AAA283422) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA283422 ELISA Kit recognizes Human ARL6IP5. It is sometimes possible for the material contained within the vial of "PRA1 family protein 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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