ADP-ribosylation factor 5 Recombinant Protein | ARF5 recombinant protein
Recombinant Human ADP-ribosylation factor 5 protein
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010]
Uniprot Description
ARF5: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.
Protein type: Motility/polarity/chemotaxis; G protein, monomeric; G protein, monomeric, ARF; G protein
Chromosomal Location of Human Ortholog: 7q31.3
Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; plasma membrane
Molecular Function: GTP binding; GTPase activity; protein binding
Biological Process: protein transport; small GTPase mediated signal transduction; vesicle-mediated transport