Apolipoprotein D Recombinant Protein
Apolipoprotein D, Recombinant, Human (Apo D)
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kD
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kD
Stability: Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
Uniprot Description
APOD: APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. Belongs to the calycin superfamily. Lipocalin family.
Protein type: Lipid-binding; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: extracellular space; cell soma; endoplasmic reticulum; perinuclear region of cytoplasm; dendrite; extracellular region
Molecular Function: lipid transporter activity; protein binding; cholesterol binding
Biological Process: response to drug; negative regulation of smooth muscle cell proliferation; negative regulation of focal adhesion formation; glucose metabolic process; negative regulation of protein import into nucleus; lipid transport; axon regeneration in the peripheral nervous system; response to reactive oxygen species; tissue regeneration; brain development; angiogenesis; lipid metabolic process; response to axon injury; aging