Western Blot (WB)
(Western blot analysis of lysates from K562, LNCaP, PC-3 cell line, mouse brain, mouse kidney, rat liver tissue lysate (from left to right), using CD164 Antibody (C-term). MBS9206998 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit CD164 Polyclonal Antibody | anti-CD164 antibody
CD164 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from K562, LNCaP, PC-3 cell line, mouse brain, mouse kidney, rat liver tissue lysate (from left to right), using CD164 Antibody (C-term). MBS9206998 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from K562, LNCaP, PC-3 cell line, mouse brain, mouse kidney, rat liver tissue lysate (from left to right), using CD164 Antibody (C-term). MBS9206998 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Zannettino A.C.W.,et al.Blood 92:2613-2628(1998).
Doyonnas R.,et al.J. Immunol. 165:840-851(2000).
Chan J.Y.-H.,et al.J. Biol. Chem. 276:2139-2152(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
NCBI and Uniprot Product Information
NCBI Description
Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008]
Uniprot Description
CD164: Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. Belongs to the CD164 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: integral to plasma membrane; lysosome; lysosomal membrane; plasma membrane; extracellular region; endosome membrane; endosome
Molecular Function: protein binding
Biological Process: heterophilic cell adhesion; negative regulation of cell proliferation; muscle development; multicellular organismal development; hemopoiesis; immune response; negative regulation of cell adhesion; cell adhesion; signal transduction
Research Articles on CD164
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Product Notes
The CD164 cd164 (Catalog #AAA9206998) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD164 Antibody (C-term) reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD164 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CD164 cd164 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD164, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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