Rabbit anti-Human SFTPC Polyclonal Antibody | anti-sftpc antibody

SFTPC, CT (SFTPC, SFTP2, Pulmonary surfactant-associated protein C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5)

Cat. Num. AAA6006240

• Gene Names: sftpc; SPC; SP-C; psp-c; sftp2; surfc; xSP-C
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SFTPC; Polyclonal Antibody; CT (SFTPC; SFTP2; Pulmonary surfactant-associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SP5); Anti -SFTPC; anti-sftpc antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-sftpc antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunofluorescence: 1:10-50; Immunohistochemistry: 1:10-50
• Immunogen: SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-173 amino acids from the C-terminal region of human SFTPC.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in Jurkat cell line lysates (35ug/lane) using MBS6006240. This demonstrates that MBS6006240 detected the SFTPC protein (arrow).)

Testing Data

(All lanes: MBS6006240 (1:2000) Lane 1: human lung lysates Lane 2: K562 whole cell lysates Lysates/proteins (20ug/lane). Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size: 21kD Blocking/Dilution buffer: 5% NFDM/TBST.)

Testing Data

Immunofluorescence (IF)

(Confocal immunofluorescent analysis with HepG2 cells using MBS6006240 followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)

Related Product Information for anti-sftpc antibody

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Product Categories/Family for anti-sftpc antibody

Antibodies; Abs to Pulmonary Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 189442527
• NCBI GeneID: 100038236
• NCBI Official Full Name: sftpc protein
• NCBI Official Synonym Full Names: surfactant, pulmonary-associated protein C
• NCBI Official Symbol: sftpc
• NCBI Official Synonym Symbols: SPC; SP-C; psp-c; sftp2; surfc; xSP-C
• NCBI Protein Information: pulmonary surfactant-associated protein C
• Protein Family: Pulmonary surfactant-associated protein