Human NAD (P)H-hydrate epimerase ELISA Kit | APOA1BP elisa kit

Human NAD (P)H-hydrate epimerase ELISA Kit

Cat. Num. AAA9426475

• Gene Names: NAXE; AIBP; PEBEL; YJEFN1; APOA1BP
• Reactivity: Human
• Synonyms: NAD (P)H-hydrate epimerase; Human NAD (P)H-hydrate epimerase ELISA Kit; 5.1.99.6; Apolipoprotein A-I-binding protein; AI-BP; NAD (P)HX epimerase; YjeF N-terminal domain-containing protein 1; YjeF_N1; APOA1BP; AIBP; YJEFN1; APOA1BP elisa kit

• Reactivity: Human

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Detection Range: 0.15 ng/mL-10.0 ng/mL
• Sensitivity: Less than 0.1ng/mL
• Assay Time: 3-5h
• Sample Volume: 100T
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 4 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 91984773
• NCBI GeneID: 128240
• NCBI Accession #: NP_658985.2
• NCBI GenBank Nucleotide #: NM_144772.2
• UniProt Accession #: Q8NCW5; Q496C6; Q5T3I2; B4DGY3
• Molecular Weight: 20,431 Da
• NCBI Official Full Name: NAD(P)H-hydrate epimerase
• NCBI Official Synonym Full Names: NAD(P)HX epimerase
• NCBI Official Symbol: NAXE
• NCBI Official Synonym Symbols: AIBP; PEBEL; YJEFN1; APOA1BP
• NCBI Protein Information: NAD(P)H-hydrate epimerase
• UniProt Protein Name: NAD(P)H-hydrate epimerase
• UniProt Gene Name: NAXE
• UniProt Synonym Gene Names: YjeF_N1

NCBI Description

The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes. [provided by RefSeq, Jul 2008]

Uniprot Description

APOA1BP: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Belongs to the nnrE/AIBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 5.1.99.6; Mitochondrial

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: cytosol; extracellular region; extracellular space; intracellular membrane-bound organelle; mitochondrial matrix; mitochondrion; nucleoplasm

Molecular Function: protein binding

Biological Process: NADH metabolic process; NADP metabolic process; nicotinamide nucleotide metabolic process

Disease: Encephalopathy, Progressive, Early-onset, With Brain Edema And/or Leukoencephalopathy