Human adaptor-related protein complex 1, beta 1 subunit ELISA Kit | AP1B1 elisa kit
Human AP-1 complex subunit beta-1, AP1B1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
AP1B1: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Belongs to the adaptor complexes large subunit family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: Golgi membrane; cytoplasmic vesicle membrane; clathrin adaptor complex; lysosomal membrane; clathrin coated vesicle membrane; trans-Golgi network membrane; cytosol
Molecular Function: protein binding; transporter activity; protein kinase binding; protein transporter activity
Biological Process: intracellular protein transport; viral reproduction; antigen processing and presentation of exogenous peptide antigen via MHC class II; post-Golgi vesicle-mediated transport; regulation of defense response to virus by virus
Research Articles on AP1B1
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Product Notes
The Human AP1B1 ap1b1 (Catalog #AAA9343406) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343406 ELISA Kit recognizes Human AP1B1. It is sometimes possible for the material contained within the vial of "adaptor-related protein complex 1, beta 1 subunit, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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