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Western Blot (WB) (Analysis of extracts of various cell lines, using RNASEH2B antibody (MBS8503894) at 1:3000 dilution.Secondary Antibody: HRP Goat Anti-Rabbit IgG (H+L) (ASO14)at 1:1000 dilution Lysates/ proteins: 25 ug per lane Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit(RM00020)Exposure time: 10s)

RNASEH2B Antibody | anti-RNASEH2B antibody

RNASEH2B Antibody

Gene Names
RNASEH2B; AGS2; DLEU8
Synonyms
RNASEH2B; RNASEH2B Antibody; anti-RNASEH2B antibody
Ordering
For Research Use Only!
Sequence Length
257

Western Blot (WB)

(Analysis of extracts of various cell lines, using RNASEH2B antibody (MBS8503894) at 1:3000 dilution.Secondary Antibody: HRP Goat Anti-Rabbit IgG (H+L) (ASO14)at 1:1000 dilution Lysates/ proteins: 25 ug per lane Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit(RM00020)Exposure time: 10s)

Western Blot (WB) (Analysis of extracts of various cell lines, using RNASEH2B antibody (MBS8503894) at 1:3000 dilution.Secondary Antibody: HRP Goat Anti-Rabbit IgG (H+L) (ASO14)at 1:1000 dilution Lysates/ proteins: 25 ug per lane Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit(RM00020)Exposure time: 10s)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,005 Da
NCBI Official Full Name
ribonuclease H2 subunit B isoform 2
NCBI Official Synonym Full Names
ribonuclease H2 subunit B
NCBI Official Symbol
RNASEH2B
NCBI Official Synonym Symbols
AGS2; DLEU8
NCBI Protein Information
ribonuclease H2 subunit B
UniProt Protein Name
Ribonuclease H2 subunit B
Protein Family
UniProt Gene Name
RNASEH2B
UniProt Synonym Gene Names
DLEU8; RNase H2 subunit B; AGS2

NCBI Description

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]

Uniprot Description

Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Research Articles on RNASEH2B

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Product Notes

The RNASEH2B rnaseh2b (Catalog #AAA8503894) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RNASEH2B, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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