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Western Blot (WB)
(Western Blot analysis of AD293, Hela cells using CBP Polyclonal Antibody at dilution of 1:1000.)
Lysine Acetyltransferase Antibody Kit
Lysine Acetyltransferase Antibody Sampler Kit
Applications
Western Blot
Synonyms
Lysine Acetyltransferase; Lysine Acetyltransferase Antibody Sampler Kit; Lysine Acetyltransferase antibody kit
Sequence Length
370
Applicable Applications for Lysine Acetyltransferase antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of AD293, Hela cells using CBP Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of AD293, Hela cells using CBP Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of HeLa cells using CBP (Acetyl Lys1535) Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of HeLa cells using CBP (Acetyl Lys1535) Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of COLO205 cells with PCAF Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of COLO205 cells with PCAF Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of Hela cells using GCN5 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of Hela cells using GCN5 Polyclonal Antibody at dilution of 1:1000.)
Related Product Information for Lysine Acetyltransferase antibody kit
Background: CREB-binding protein (CBP) and p300 are highly conserved and functionally related transcriptional co-activators that associate with transcriptional regulators and signaling molecules, integrating multiple signal transduction pathways with the transcriptional machinery. CBP/p300 also contain histone acetyltransferase (HAT) activity, allowing them to acetylate histones and other proteins. The role of acetylation of CBP/p300 is of particular interest. Acetylation of p300 at Lys1499 has been demonstrated to enhance its HAT activity and affect a wide variety of signaling events. p300/CBP-associated factor (PCAF), also known as lysine acetyl-transferase 2B (KAT2B), and General Control of Amino Acid Synthesis Yeast Homolog Like 2 (GCN5L2) are transcriptional adaptor proteins in addition to HATs. PCAF functions as the catalytic subunit of the PCAF transcriptional co-activator complex. GCN5L2 functions as the catalytic subunit of the STAGA and TFTC transcription coactivator complexes. PCAF and GCN5L2 acetylate histone H3 at Lys14 and histone H4 at Lys8, both of which contribute to gene activation by modulating chromatin structure and recruiting additional co-activator proteins that contain acetyl-lysine binding bromo-domains. PCAF also acetylates non-histone proteins including transcriptional activators (p53, E2F1, MyoD) and general transcription factors (TFIIEbeta and TFIIF). GCN5L2 also acetylates non-histone proteins such as transcription activators (TAT, c-Myb), transcription co-activators (PGC1-alpha), and nuclear receptors (Steroidogenic Factor 1). Acetylation of these proteins regulates their nuclear localization, protein stability, DNA binding, and co- activator association.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
Lysine acetyltransferase
Protein Family
Similar Products
Product Notes
The Lysine Acetyltransferase (Catalog #AAA2550109) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Lysine Acetyltransferase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Lysine Acetyltransferase for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lysine Acetyltransferase, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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