Phosphomannomutase/phosphoglucomutase (algC) Recombinant Protein | algC recombinant protein
Recombinant Pseudomonas aeruginosa Phosphomannomutase/phosphoglucomutase (algC)
NCBI and Uniprot Product Information
Uniprot Description
Highly reversible phosphoryltransferase. The phosphomannomutase activity produces a precursor for alginate polymerization, the alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core lipopolysaccaride (LPS) biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production, an exoproduct correlated with pathogenicity (PubMed:10481091). Required for biofilm production. The reaction proceeds via 2 processive phosphoryl transferase reactions; first from enzyme-phospho-Ser-108 to the substrate (generating a bisphosphorylated substrate intermediate and a dephosphorylated enzyme), a 180 degree rotation of the intermediate (probably aided by movement of domain 4), and subsequent transfer of phosphate back to the enzyme (PubMed:11716469, PubMed:16880541, PubMed:16595672, PubMed:22242625).
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Product Notes
The algC algc (Catalog #AAA1215215) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-463, Full length protein. The amino acid sequence is listed below: STAKAPTLPA SIFRAYDIRG VVGDTLTAET AYWIGRAIGS ESLARGEPCV AVGRDGRLSG PELVKQLIQG LVDCGCQVSD VGMVPTPVLY YAANVLEGKS GVMLTGSHNP PDYNGFKIVV AGETLANEQI QALRERIEKN DLASGVGSVE QVDILPRYFK QIRDDIAMAK PMKVVVDCGN GVAGVIAPQL IEALGCSVIP LYCEVDGNFP NHHPDPGKPE NLKDLIAKVK AENADLGLAF DGDGDRVGVV TNTGTIIYPD RLLMLFAKDV VSRNPGADII FDVKCTRRLI ALISGYGGRP VMWKTGHSLI KKKMKETGAL LAGEMSGHVF FKERWFGFDD GIYSAARLLE ILSQDQRDSE HVFSAFPSDI STPEINITVT EDSKFAIIEA LQRDAQWGEG NITTLDGVRV DYPKGWGLVR ASNTTPVLVL RFEADTEEEL ERIKTVFRNQ LKAVDSSLPV PF. It is sometimes possible for the material contained within the vial of "Phosphomannomutase/phosphoglucomutase (algC), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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