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SDS-Page

Urotensin 2 (UST2) Recombinant Protein | UST2 recombinant protein

Recombinant Urotensin 2 (UST2)

Gene Names
UTS2; UII; U-II; UCN2; PRO1068
Applications
SDS-Page, Western Blot, ELISA, Immunoprecipitation
Purity
> 95%
Synonyms
Urotensin 2 (UST2); Recombinant Urotensin 2 (UST2); UST2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- S LPLLDSREIS FQLSAPHEDA RLTPEELERA SLLQILPEML GAERGDILRK ADSSTNIFNP RGNLRKFQDF SGQDPNILLS HLLARIWKPY KKRETPDCFW
Sequence Length
124
Applicable Applications for UST2 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Organism
Homo sapiens (Human)
Expression System
Prokaryotic expression
Residues
Ser20~Trp120 (Accession # O95399) with N-terminal His-Tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

SDS-Page

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13.2kDa
NCBI Official Full Name
urotensin-2 isoform b preproprotein
NCBI Official Synonym Full Names
urotensin 2
NCBI Official Symbol
UTS2
NCBI Official Synonym Symbols
UII; U-II; UCN2; PRO1068
NCBI Protein Information
urotensin-2; prepro U-II; urotensin II
UniProt Protein Name
Urotensin-2
UniProt Gene Name
UTS2
UniProt Synonym Gene Names
U-II; UII
UniProt Entry Name
UTS2_HUMAN

NCBI Description

This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

UTS2: Highly potent vasoconstrictor. Belongs to the urotensin-2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: extracellular space; extracellular region

Molecular Function: hormone activity; receptor binding

Biological Process: response to drug; positive regulation of synaptic transmission, cholinergic; positive regulation of circadian sleep/wake cycle, REM sleep; negative regulation of heart rate; negative regulation of glomerular filtration; positive regulation of collagen biosynthetic process; positive regulation of heart rate; response to testosterone stimulus; positive regulation of vasodilation; negative regulation of insulin secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; positive regulation of angiogenesis; positive regulation of fibroblast proliferation; muscle contraction; regulation of blood pressure; response to hypoxia; negative regulation of blood pressure; positive regulation of cell differentiation; positive regulation of blood pressure

Research Articles on UST2

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Product Notes

The UST2 uts2 (Catalog #AAA2018612) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Urotensin 2 (UST2) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the UST2 uts2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG SEF- S LPLLDSREIS FQLSAPHEDA RLTPEELERA SLLQILPEML GAERGDILRK ADSSTNIFNP RGNLRKFQDF SGQDPNILLS HLLARIWKPY KKRETPDCFW. It is sometimes possible for the material contained within the vial of "Urotensin 2 (UST2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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