Mouse aldehyde dehydrogenase 3 family, member A2 ELISA Kit | ALDH3A2 elisa kit
Mouse Fatty aldehyde dehydrogenase, ALDH3A2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ALDH3A2: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - butanoate; Mitochondrial; Amino Acid Metabolism - histidine; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - ascorbate and aldarate; Oxidoreductase; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - beta-alanine; EC 1.2.1.3; Membrane protein, integral; Amino Acid Metabolism - tryptophan; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - propanoate
Cellular Component: intracellular membrane-bound organelle; membrane; mitochondrion; endoplasmic reticulum; mitochondrial inner membrane; integral to membrane; peroxisome; nucleus; cytosol
Molecular Function: long-chain-alcohol oxidase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; 3-chloroallyl aldehyde dehydrogenase activity; long-chain-aldehyde dehydrogenase activity; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process: phytol metabolic process; epidermis development; response to reactive oxygen species; central nervous system development; metabolic process; formaldehyde metabolic process; aldehyde metabolic process; sesquiterpenoid metabolic process; peripheral nervous system development
Research Articles on ALDH3A2
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Product Notes
The Mouse ALDH3A2 aldh3a2 (Catalog #AAA9316835) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316835 ELISA Kit recognizes Mouse ALDH3A2. It is sometimes possible for the material contained within the vial of "aldehyde dehydrogenase 3 family, member A2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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