Typical Testing Data/Standard Curve (for reference only)
Delta-aminolevulinic acid dehydratase ELISA Kit | Alad elisa kit
Rat Delta-aminolevulinic acid dehydratase ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
catalyzes the conversion of 5-aminolevulinate to porphobilinogen in heme biosynthesis [RGD, Feb 2006]
Uniprot Description
ALAD: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. Defects in ALAD are the cause of acute hepatic porphyria (AHEPP). A form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors. Belongs to the ALADH family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 4.2.1.24; Lyase
Cellular Component: cytosol; extracellular space; nucleus
Molecular Function: identical protein binding; lead ion binding; porphobilinogen synthase activity; zinc ion binding
Biological Process: heme biosynthetic process; protein homooligomerization; protoporphyrinogen IX biosynthetic process; response to activity; response to aluminum ion; response to amino acid stimulus; response to arsenic; response to cadmium ion; response to cobalt ion; response to drug; response to ethanol; response to glucocorticoid stimulus; response to herbicide; response to hormone stimulus; response to hypoxia; response to inorganic substance; response to ionizing radiation; response to iron ion; response to lead ion; response to lipopolysaccharide; response to mercury ion; response to metal ion; response to methylmercury; response to nutrient; response to nutrient levels; response to organic cyclic substance; response to organic substance; response to oxidative stress; response to selenium ion; response to toxin; response to vitamin; response to vitamin B1; response to vitamin E; response to zinc ion
Research Articles on Alad
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Product Notes
The Rat Alad alad (Catalog #AAA289615) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289615 ELISA Kit recognizes Rat Alad. It is sometimes possible for the material contained within the vial of "Delta-aminolevulinic acid dehydratase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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