Testing Data
(The TFact GATA6 DNA-Binding ELISA detects active GATA6 in Jurkat and Hela Nuclear Extract. The Jurkat and Hela cells were grown 3 days in RPMI 1640 and DMEM with 10% FBS and harvested for nuclear extract.)
GATA6 elisa kit
GATA6 TFact DNA-Binding ELISA Kit
Testing Data
(The TFact GATA6 DNA-Binding ELISA detects active GATA6 in Jurkat and Hela Nuclear Extract. The Jurkat and Hela cells were grown 3 days in RPMI 1640 and DMEM with 10% FBS and harvested for nuclear extract.)
Testing Data
(The TFact GATA6 DNA-Binding ELISA detects active GATA6 in Jurkat and Hela Nuclear Extract. The Jurkat and Hela cells were grown 3 days in RPMI 1640 and DMEM with 10% FBS and harvested for nuclear extract.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012]
Uniprot Description
GATA6: Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Interacts with LMCD1. Expressed in heart, gut and gut-derived tissues. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Motility/polarity/chemotaxis; Transcription factor
Chromosomal Location of Human Ortholog: 18q11.2
Cellular Component: nuclear membrane; nucleoplasm; nucleus; transcription factor complex
Molecular Function: chromatin binding; DNA binding transcription factor activity; protein binding; protein kinase binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; transcription factor binding; transcription regulatory region DNA binding; zinc ion binding
Biological Process: animal organ formation; blood coagulation; cardiac muscle cell differentiation; cardiac muscle hypertrophy in response to stress; cellular protein metabolic process; cellular response to BMP stimulus; cellular response to gonadotropin stimulus; cellular response to hypoxia; endodermal cell fate determination; in utero embryonic development; liver development; male gonad development; negative regulation of apoptosis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of transforming growth factor beta1 production; negative regulation of transforming growth factor-beta2 production; outflow tract septum morphogenesis; pancreatic A cell differentiation; phospholipid metabolic process; positive regulation of angiogenesis; positive regulation of BMP signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of cardiac muscle myoblast proliferation; positive regulation of cardioblast differentiation; positive regulation of cell cycle arrest; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; response to drug; response to estrogen; smooth muscle cell differentiation; transcription from RNA polymerase II promoter; tube morphogenesis; type B pancreatic cell differentiation
Disease: Atrial Septal Defect 9; Atrioventricular Septal Defect 5; Conotruncal Heart Malformations; Heart Defects, Congenital, And Other Congenital Anomalies; Tetralogy Of Fallot
Research Articles on GATA6
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Product Notes
The Human, Mouse, Rat GATA6 gata6 (Catalog #AAA9502186) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502186 ELISA Kit recognizes Human, Mouse, Rat GATA6. It is sometimes possible for the material contained within the vial of "GATA6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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