Afadin (MLLT4) Recombinant Protein | MLLT4 recombinant protein

Recombinant Human Afadin (MLLT4) , partial

• Gene Names: AFDN; AF6; MLLT4; MLL-AF6; l-afadin
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Afadin (MLLT4); Recombinant Human Afadin (MLLT4); partial; MLLT4 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1651

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 90819233
• NCBI GeneID: 4301
• NCBI Accession #: NP_001035089.1
• NCBI GenBank Nucleotide #: NM_001040000.2
• UniProt Accession #: P55196; O75087; O75088; O75089; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92
• Molecular Weight: 207,788 Da
• NCBI Official Full Name: afadin isoform 2
• NCBI Official Synonym Full Names: afadin, adherens junction formation factor
• NCBI Official Symbol: AFDN
• NCBI Official Synonym Symbols: AF6; MLLT4; MLL-AF6; l-afadin
• NCBI Protein Information: afadin
• UniProt Protein Name: Afadin
• UniProt Gene Name: AFDN
• UniProt Synonym Gene Names: Protein AF-6

NCBI Description

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]

Uniprot Description

Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.