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Western Blot (WB) (Western blot analysis of extracts of Mouse hippocampal tissue sample, using Phospho-Afadin (Tyr1230) Antibody.((13174))

Rabbit Afadin Polyclonal Antibody | anti-AFDN antibody

Afadin (Phospho-Tyr1230) Antibody

Gene Names
AFDN; AF6; MLLT4; MLL-AF6; l-afadin
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Synonyms
Afadin; Polyclonal Antibody; Afadin (Phospho-Tyr1230) Antibody; AF6; AFAD_HUMAN; ALL1-fused gene from chromosome 6 protein; Mllt4; Protein Af-6; Protein AF6;; anti-AFDN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Phospho-Afadin (Phospho-Tyr1230) Antibody detects endogenous levels of Afadin only when phosphorylated at Tyr1230
Purity/Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
1651
Applicable Applications for anti-AFDN antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human Afadin around the phosphorylation site of Tyr1230
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of extracts of Mouse hippocampal tissue sample, using Phospho-Afadin (Tyr1230) Antibody.((13174))

Western Blot (WB) (Western blot analysis of extracts of Mouse hippocampal tissue sample, using Phospho-Afadin (Tyr1230) Antibody.((13174))
Product Categories/Family for anti-AFDN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
207
NCBI Official Full Name
afadin isoform 2
NCBI Official Synonym Full Names
afadin, adherens junction formation factor
NCBI Official Symbol
AFDN
NCBI Official Synonym Symbols
AF6; MLLT4; MLL-AF6; l-afadin
NCBI Protein Information
afadin
UniProt Protein Name
Afadin
Protein Family
UniProt Gene Name
AFDN
UniProt Synonym Gene Names
Protein AF-6

NCBI Description

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]

Uniprot Description

Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.

Research Articles on AFDN

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Product Notes

The AFDN afdn (Catalog #AAA9429326) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Afadin (Phospho-Tyr1230) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Afadin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the AFDN afdn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Afadin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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