Rat Alpha-1A adrenergic receptor ELISA Kit | Adra1a elisa kit
Rat Alpha-1A adrenergic receptor ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds adrenergic compounds and analogs; activates phospholipase C mediated signal transduction [RGD, Feb 2006]
Uniprot Description
ADRA1A: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily. 9 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR
Cellular Component: cytosol; integral to plasma membrane; membrane; nuclear membrane; nucleus; plasma membrane; T-tubule; Z disc
Molecular Function: alpha1-adrenergic receptor activity; protein heterodimerization activity
Biological Process: adult heart development; aging; cell growth; cell-cell signaling; elevation of cytosolic calcium ion concentration; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); micturition; negative regulation of heart rate in baroreceptor response to increased systemic arterial blood pressure; negative regulation of Rho protein signal transduction; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; organ growth; phospholipase C activation; positive regulation of action potential; positive regulation of heart rate; positive regulation of heart rate by epinephrine-norepinephrine; positive regulation of MAPKKK cascade; positive regulation of smooth muscle contraction; positive regulation of synaptic transmission, GABAergic; positive regulation of systemic arterial blood pressure; positive regulation of the force of heart contraction by epinephrine-norepinephrine; positive regulation of vasoconstriction; response to drug; response to hormone stimulus
Research Articles on Adra1a
Similar Products
Product Notes
The Rat Adra1a adra1a (Catalog #AAA2886158) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886158 ELISA Kit recognizes Rat Adra1a. It is sometimes possible for the material contained within the vial of "Alpha-1A adrenergic receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.