Human Alcohol dehydrogenase 1A ELISA Kit | ADH1A elisa kit

Human Alcohol dehydrogenase 1A ELISA Kit

Cat. Num. AAA9425957

• Gene Names: ADH1A; ADH1
• Reactivity: Human
• Synonyms: Alcohol dehydrogenase 1A; Human Alcohol dehydrogenase 1A ELISA Kit; Alcohol dehydrogenase subunit alpha; ADH1A; ADH1; 1.1.1.1; ADH1A elisa kit

• Reactivity: Human

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Detection Range: 0.312-20 ng/mL
• Sensitivity: Less than 0.1ng/mL
• Assay Time: 3-5h
• Sample Volume: 50T
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 4 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 4501929
• NCBI GeneID: 124
• NCBI Accession #: NP_000658.1
• NCBI GenBank Nucleotide #: NM_000667.3
• UniProt Accession #: P07327; Q17R68; A8K3E3
• Molecular Weight: 39,859 Da
• NCBI Official Full Name: alcohol dehydrogenase 1A
• NCBI Official Synonym Full Names: alcohol dehydrogenase 1A (class I), alpha polypeptide
• NCBI Official Symbol: ADH1A
• NCBI Official Synonym Symbols: ADH1
• NCBI Protein Information: alcohol dehydrogenase 1A
• UniProt Protein Name: Alcohol dehydrogenase 1A
• Protein Family: Alcohol dehydrogenase
• UniProt Gene Name: ADH1A
• UniProt Synonym Gene Names: ADH1

NCBI Description

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Uniprot Description

ADH1A: a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Transcription regulation; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 4q23

Cellular Component: cytosol; nucleoplasm; plasma membrane

Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; protein binding; retinol dehydrogenase activity

Biological Process: drug metabolic process; ethanol oxidation