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Typical Testing Data/Standard Curve (for reference only)

Human Pituitary adenylate cyclase-activating polypeptide type I receptor ELISA Kit | ADCYAP1R1 elisa kit

Human Pituitary adenylate cyclase-activating polypeptide type I receptor ELISA Kit

Gene Names
ADCYAP1R1; PAC1; PAC1R; PACAPR; PACAPRI
Reactivity
Human
Synonyms
Pituitary adenylate cyclase-activating polypeptide type I receptor; Human Pituitary adenylate cyclase-activating polypeptide type I receptor ELISA Kit; PACAP type I receptor; PACAP-R-1; PACAP-R1; ADCYAP1R1; ADCYAP1R1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
468
Assay Type
Sandwich
Detection Range
0.156-10 ng/mL
Sensitivity
0.078 ng/ml
Intra-Assay CV
<=6.2%
Inter-Assay CV
<=8.6%
Recovery
102%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
117
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,957 Da
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide type I receptor isoform 3
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
NCBI Official Symbol
ADCYAP1R1
NCBI Official Synonym Symbols
PAC1; PAC1R; PACAPR; PACAPRI
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide type I receptor
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide type I receptor
UniProt Gene Name
ADCYAP1R1
UniProt Synonym Gene Names
PACAP type I receptor; PACAP-R-1; PACAP-R1
UniProt Entry Name
PACR_HUMAN

NCBI Description

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]

Uniprot Description

ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7p14

Cellular Component: caveola; cell surface; endosome; integral to plasma membrane; neuron projection; plasma membrane; receptor complex; rough endoplasmic reticulum; tight junction

Molecular Function: adenylate cyclase binding; ADP-ribosylation factor binding; neuropeptide binding; protein binding; receptor activity; vasoactive intestinal polypeptide receptor activity

Biological Process: adenylate cyclase activation; cAMP-mediated signaling; cell differentiation; cell surface receptor linked signal transduction; development of primary female sexual characteristics; G-protein coupled receptor protein signaling pathway; multicellular organismal response to stress; nerve growth factor receptor signaling pathway; phospholipase C activation; response to drug; response to estradiol stimulus; response to ethanol; spermatogenesis; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on ADCYAP1R1

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Product Notes

The Human ADCYAP1R1 adcyap1r1 (Catalog #AAA2883666) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883666 ELISA Kit recognizes Human ADCYAP1R1. It is sometimes possible for the material contained within the vial of "Pituitary adenylate cyclase-activating polypeptide type I receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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