Human Pituitary adenylate cyclase-activating polypeptide type I receptor ELISA Kit | ADCYAP1R1 elisa kit
Human Pituitary adenylate cyclase-activating polypeptide type I receptor ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Uniprot Description
ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; GPCR, family 2; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p14
Cellular Component: caveola; cell surface; endosome; integral to plasma membrane; neuron projection; plasma membrane; receptor complex; rough endoplasmic reticulum; tight junction
Molecular Function: adenylate cyclase binding; ADP-ribosylation factor binding; neuropeptide binding; protein binding; receptor activity; vasoactive intestinal polypeptide receptor activity
Biological Process: adenylate cyclase activation; cAMP-mediated signaling; cell differentiation; cell surface receptor linked signal transduction; development of primary female sexual characteristics; G-protein coupled receptor protein signaling pathway; multicellular organismal response to stress; nerve growth factor receptor signaling pathway; phospholipase C activation; response to drug; response to estradiol stimulus; response to ethanol; spermatogenesis; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on ADCYAP1R1
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Product Notes
The Human ADCYAP1R1 adcyap1r1 (Catalog #AAA2883666) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883666 ELISA Kit recognizes Human ADCYAP1R1. It is sometimes possible for the material contained within the vial of "Pituitary adenylate cyclase-activating polypeptide type I receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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