Human A disintegrin and metalloproteinase with thrombospondin motifs 6 ELISA Kit | ADAMTS6 elisa kit

Human A disintegrin and metalloproteinase with thrombospondin motifs 6 ELISA Kit

Cat. Num. AAA762697

• Gene Names: ADAMTS6; ADAM-TS6; ADAMTS-6; ADAM-TS 6
• Reactivity: Human
• Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 6; Human A disintegrin and metalloproteinase with thrombospondin motifs 6 ELISA Kit; ADAMTS6/A disintegrin and metalloproteinase with thrombospondin motifs 6/ADAM-TS 6/ADAM-TS6/ADAMTS-6; ADAMTS6 elisa kit

• Reactivity: Human
• Sequence Length: 1117

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich ELISA, Double Antibody
• Detection Range: 31.2-2000pg/ml
• Sensitivity: 18.75pg/ml
• Preparation and Storage: Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).

Typical Testing Data

Typical Standard Curve

Related Product Information for ADAMTS6 elisa kit

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human ADAMTS6 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human ADAMTS6 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and wash with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Human ADAMTS6 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of Human ADAMTS6 can be calculated.

NCBI and Uniprot Product Information

• NCBI GI #: 64276808
• NCBI GeneID: 11174
• NCBI Accession #: NP_922932.2
• NCBI GenBank Nucleotide #: NM_197941.2
• Molecular Weight: 34,189 Da
• NCBI Official Full Name: A disintegrin and metalloproteinase with thrombospondin motifs 6 preproprotein
• NCBI Official Synonym Full Names: ADAM metallopeptidase with thrombospondin type 1 motif 6
• NCBI Official Symbol: ADAMTS6
• NCBI Official Synonym Symbols: ADAM-TS6; ADAMTS-6; ADAM-TS 6
• NCBI Protein Information: A disintegrin and metalloproteinase with thrombospondin motifs 6
• UniProt Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 6
• Protein Family: A disintegrin and metalloproteinase with thrombospondin motifs
• UniProt Gene Name: ADAMTS6
• UniProt Synonym Gene Names: ADAM-TS 6; ADAM-TS6; ADAMTS-6
• UniProt Entry Name: ATS6_HUMAN

NCBI Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

Uniprot Description

ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

Protein type: Protease; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 5q12

Cellular Component: proteinaceous extracellular matrix

Molecular Function: metalloendopeptidase activity; metallopeptidase activity; zinc ion binding

Biological Process: proteolysis