Serum Gonadotropin Active Protein
Pregnant Mare Serum Gonadotropin (PMSG)
Synonyms
Serum Gonadotropin; Pregnant Mare Serum Gonadotropin (PMSG); PMSG; Serum Gonadotropin active protein
Form/Format
Lyophilized powder
Source
Equine Serum
Appearance
White to off white solid
Solubility
Clear, colorless (1 mL/5000 IU in water)
Activity
> 2,4000 IU/vial
Reconstitution
Reconstitute as 1mL/5000 U vial in deionized water. Further dilutions should be in a buffer such as tris buffered saline with 1% BSA as a carrier.
Handling
Handle as a potentially hazardous substance.
CAS number
9002-70-4
E.C. number
232-663-9
Preparation and Storage
Ships on blue ice.
Store at 2-8°C
Protect from air and light.
Store at 2-8°C
Protect from air and light.
Related Product Information for Serum Gonadotropin active protein
Custom preparations, technical support, bulk quantities and aliquoting available.
Equine chorionic gonadotropin (eCG) is a gonadotropic hormone produced in the chorion of pregnant mares. Most commonly called pregnant mare's serum gonadotropin (PMSG) in the past, the hormone is commonly used in concert with progestogen to induce ovulation in livestock prior to artificial insemination.
Pregnant mares secrete the hormone from their endometrial cups between 40 and 130 days in to their gestation, and once collected, it has been used to artificially induce estrus in female sheep, goats, cattle, and swine. Despite being less pure than pituitary extracts from sheep, goats or swine, PMSG tends to be used because of its longer circulatory half-life. PMSG is marked by the fact that it produces both follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Equine CG, like all glycoprotein hormones, is composed of two dissimilar subunits named alpha and beta. The alpha subunit is common to all glycoprotein hormones (LH, FSH, TSH, CG). The beta subunit is specific and is responsible for receptor binding specificity. Nevertheless, in the equidaes (horses, donkeys, zebras), the placental CGs also have the same beta subunit as the pituitary LHs. Consequently, in these species CGs differ from LHs only by their carbohydrate side-chains (particularly in their respective beta subunits).
Equine chorionic gonadotropin (eCG) is a gonadotropic hormone produced in the chorion of pregnant mares. Most commonly called pregnant mare's serum gonadotropin (PMSG) in the past, the hormone is commonly used in concert with progestogen to induce ovulation in livestock prior to artificial insemination.
Pregnant mares secrete the hormone from their endometrial cups between 40 and 130 days in to their gestation, and once collected, it has been used to artificially induce estrus in female sheep, goats, cattle, and swine. Despite being less pure than pituitary extracts from sheep, goats or swine, PMSG tends to be used because of its longer circulatory half-life. PMSG is marked by the fact that it produces both follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Equine CG, like all glycoprotein hormones, is composed of two dissimilar subunits named alpha and beta. The alpha subunit is common to all glycoprotein hormones (LH, FSH, TSH, CG). The beta subunit is specific and is responsible for receptor binding specificity. Nevertheless, in the equidaes (horses, donkeys, zebras), the placental CGs also have the same beta subunit as the pituitary LHs. Consequently, in these species CGs differ from LHs only by their carbohydrate side-chains (particularly in their respective beta subunits).
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Product Notes
The Serum Gonadotropin (Catalog #AAA173236) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Serum Gonadotropin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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