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PROLACTIN Active Protein | PRL active protein

RECOMBINANT HUMAN PROLACTIN

Applications
Functional Assay
Purity
>98% by SDS PAGE and HPLC analysis
Synonyms
PROLACTIN; RECOMBINANT HUMAN PROLACTIN; PRL active protein
Ordering
For Research Use Only!
Purity/Purification
>98% by SDS PAGE and HPLC analysis
Form/Format
Purified recombinant protein - lyophilised
Concentration
Approximate Protein Concentration: 0.1mg/ml after reconstitution (varies by lot)
Sequence Length
227
Applicable Applications for PRL active protein
Functional Assays (FN)
Reconstitution
Reconstitute with 0.5ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution.
Preparation
Activity
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.
Target Species
Human
Preparation and Storage
Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 3 months from date of reconstitution.
Related Product Information for PRL active protein
Prolactin (PRL), also known as luteotropic hormone (LTH), is a neuroendocrine hormone and member of the somatotropin/prolactin family, which is secreted by the anterior pituitary, under the regulation of neuroendocrine neurons in the hypothalamus. The primary function of prolactin is the stimulation of breast development, and promotion of lactation during pregnancy and suckling, but prolactin also exhibits a weak luteotropic effect. Elevated levels of prolactin can be associated with hypothalamic disease, hypothyroidism, kidney disease, chest wall trauma or irritation, and tumours of the pituitary, including prolactinomas.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23kD (200 amino acid residues)
NCBI Official Full Name
prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
PRL
NCBI Protein Information
prolactin; decidual prolactin
UniProt Protein Name
Prolactin
Protein Family
UniProt Gene Name
PRL
UniProt Synonym Gene Names
PRL
UniProt Entry Name
PRL_HUMAN

NCBI Description

This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Uniprot Description

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: extracellular region

Molecular Function: protein binding; prolactin receptor binding; hormone activity

Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; positive regulation of JAK-STAT cascade; regulation of multicellular organism growth; female pregnancy

Research Articles on PRL

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Product Notes

The PRL prl (Catalog #AAA232520) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PROLACTIN can be used in a range of immunoassay formats including, but not limited to, Functional Assays (FN). Researchers should empirically determine the suitability of the PRL prl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PROLACTIN, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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