Interleukin 17A/F Heterodimer Active Protein | Il17f active protein
Interleukin 17A/F Heterodimer, Recombinant, Mouse (IL-17, CTLA8, IL-17A, Interleukin-17A precursor, Cytotoxic T-lymphocyte-associated antigen 8)
Gene Names
Il17f; C87042; IL-17F
Purity
Highly Purified95% by SDSPAGE under reducing conditions and visualized by silver stain.
Synonyms
Interleukin 17A/F Heterodimer; Recombinant; Mouse (IL-17; CTLA8; IL-17A; Interleukin-17A precursor; Cytotoxic T-lymphocyte-associated antigen 8); Il17f active protein
Purity/Purification
Highly Purified
95% by SDSPAGE under reducing conditions and visualized by silver stain.
95% by SDSPAGE under reducing conditions and visualized by silver stain.
Form/Format
Supplied as a lyophilized powder in 0.2um sterile-filtered solution in 30% acetonitrile, 0.1% TFA, 50ug of bBSA per 1ug of cytokine. Reconstitute with sterile 4mM HCI containing at least 0.1% HSA or BSA be added to the vial to prepare a stock solution of
Activity
Measured by its ability to stimulate induce IL-6 production by NIH/3T3 cells (Yao, Z. et al., 1995, Immunity 3:811). The ED 50 for this effect is typically 0.075-0.375ug/ml.
Endotoxin Level
1.0 EU/1ug (LAL)
Preparation and Storage
12 months from date of receipt, 20 to 70 degree C as supplied.
1 month, 2 to 8 degree C under sterile conditions after reconstitution.
3 months, 20 to 70 degree C under sterile conditions after reconstitution.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month, 2 to 8 degree C under sterile conditions after reconstitution.
3 months, 20 to 70 degree C under sterile conditions after reconstitution.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Product Categories/Family for Il17f active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
The recombinant mouse IL1-7A/IL-17F is a refolded disulfide-linked heterodimer of IL-17A and
IL-17F. The non-methionyl form of rhIL-17A monomer has a predicted molecular mass of 14.9kD whereas the methionyl form of rhIL1-7F monomer has a predicted mol
IL-17F. The non-methionyl form of rhIL-17A monomer has a predicted molecular mass of 14.9kD whereas the methionyl form of rhIL1-7F monomer has a predicted mol
NCBI Official Full Name
interleukin-17F
NCBI Official Synonym Full Names
interleukin 17F
NCBI Official Symbol
Il17f
NCBI Official Synonym Symbols
C87042; IL-17F
NCBI Protein Information
interleukin-17F
UniProt Protein Name
Interleukin-17F
Protein Family
UniProt Gene Name
Il17f
UniProt Synonym Gene Names
IL-17F
UniProt Entry Name
IL17F_MOUSE
Uniprot Description
Function: Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis
By similarity. Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. Ref.2
Subunit structure: Homodimer; disulfide-linked
By similarity.
Subcellular location: Secreted
By similarity.
Sequence similarities: Belongs to the IL-17 family.
Research Articles on Il17f
Similar Products
Product Notes
The Il17f il17f (Catalog #AAA650184) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Interleukin 17A/F Heterodimer, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
