blc active protein
BLC, Recombinant, Mouse (B-lymphocyte Chemoattractant, Mouse Equivalent of Human B Cell-Attracting Chemokine-1, BCA-1, CXCL13)
Purity
Highly Purified~98% (SDS-PAGE, HPLC). Purified by sequential chromatography.
Synonyms
BLC; Recombinant; Mouse (B-lymphocyte Chemoattractant; Mouse Equivalent of Human B Cell-Attracting Chemokine-1; BCA-1; CXCL13); blc active protein
Purity/Purification
Highly Purified
~98% (SDS-PAGE, HPLC). Purified by sequential chromatography.
~98% (SDS-PAGE, HPLC). Purified by sequential chromatography.
Form/Format
Supplied as a sterile filtered lyophilized powder, carrier free. Reconstitute in sterile, ddH2O, 0.1-1% BSA to 0.5-1mg/mL. Further dilutions should be made in aqueous buffers.
Biological Activity
The biological activity was determined by measuring dose-dependent chemotaxis with murine B lymphocytes. A concentration range of 10-100ng/ml produced significant chemotaxis. BLC, a CXC chemokine, regulates B cell migration to and within lymphoid follicles in most secondary lymphoid organs. The receptor for BLC is CXCR5.
Endotoxin Level
0.1ng/ug
Preparation and Storage
Store at -20 degree C. Reconstitute to nominal volume by adding sterile ddH2O, 0.1-1% BSA. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for blc active protein
BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes.
Product Categories/Family for blc active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
9.5kD
NCBI Official Full Name
Blc
NCBI Official Symbol
blc
NCBI Protein Information
Outer membrane lipoprotein Blc precursor
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Product Notes
The blc (Catalog #AAA650892) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BLC, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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