Structure
MHY-1485 activator
MHY-1485
Purity
>98% (TLC); NMR (conforms)
Synonyms
MHY-1485; 4; 6-Di-4-morpholinyl-N-(4-nitrophenyl)-1; 3; 5-triazin-2-amine; mTOR activator; MHY-1485 activator
Purity/Purification
>98% (TLC); NMR (conforms)
Specific Activity
Pan-kinase inhibitor
CAS Registry Number
326914-06-1
Molecular Formula
C17H21N7O4
Solubility
May be dissolved in DMSO (20mg/ml); or DMF (10mg/ml)
Preparation and Storage
Store desiccated as supplied at -20 degree C for up to 2 years. Store solutions at -20 degree C for up to two months.
Structure
Structure
Related Product Information for MHY-1485 activator
mTOR activator suppresses autophagy by inhibiting the fusion of autophagosomes with lysosomes leading to the accumulation of enlarged autophagosomes. Increases ovarian follicle development. Displays cellular protective effects from cytotoxic doses of dexamethasone or UV radiation. A useful tool for probing the cellular role of mTOR. Cell permeable.
Product Categories/Family for MHY-1485 activator
References
1. YJ Choy et al. PLoS One 2012 7(8):e43418
2. Y Cheng et al. PLoS One 2015 10(2):e0117769
3. S Zhao et al. Biochem. Biophys. Res. Commun. 2016 481:212
4. B Yang et al. Oncotarget 2017 481:212 Jan 4, Epub
5. C Li and HM Siragy Am. J. Physiol. Endocrinol. Metab. 2015 309:E302
2. Y Cheng et al. PLoS One 2015 10(2):e0117769
3. S Zhao et al. Biochem. Biophys. Res. Commun. 2016 481:212
4. B Yang et al. Oncotarget 2017 481:212 Jan 4, Epub
5. C Li and HM Siragy Am. J. Physiol. Endocrinol. Metab. 2015 309:E302
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Product Notes
The MHY-1485 (Catalog #AAA515787) is an Activator and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MHY-1485, Activator" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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