Mouse Acetyl-CoA acetyltransferase, mitochondrial ELISA Kit | Acat1 elisa kit
Mouse Acetyl-CoA acetyltransferase, mitochondrial ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ACAT1: Plays a major role in ketone body metabolism. Defects in ACAT1 are a cause of 3-ketothiolase deficiency (3KTD); also known as alpha- methylacetoaceticaciduria. 3KTD is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded. Urinary excretion of 2-methyl-3- hydroxybutyric acid, 2-methylacetoacetic acid, triglylglycine, butanone is increased. It seems likely that the severity of this disease correlates better with the environmental or acquired factors than with the ACAT1 genotype. Belongs to the thiolase family.
Protein type: Carbohydrate Metabolism - pyruvate; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Amino Acid Metabolism - lysine degradation; EC 2.3.1.9; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - tryptophan; Mitochondrial; Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid; Acetyltransferase; Amino Acid Metabolism - valine, leucine and isoleucine degradation
Cellular Component: mitochondrial inner membrane; mitochondrial matrix; mitochondrion
Molecular Function: acetyl-CoA C-acetyltransferase activity; catalytic activity; coenzyme binding; enzyme binding; metal ion binding; protein homodimerization activity; transferase activity; transferase activity, transferring acyl groups; transferase activity, transferring groups other than amino-acyl groups
Biological Process: metabolic process; protein homooligomerization
Research Articles on Acat1
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Product Notes
The Mouse Acat1 acat1 (Catalog #AAA2881746) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881746 ELISA Kit recognizes Mouse Acat1. It is sometimes possible for the material contained within the vial of "Acetyl-CoA acetyltransferase, mitochondrial, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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