Rat Acetyl-CoA acetyltransferase, mitochondrial ELISA Kit | Acat1 elisa kit
Rat Acetyl-CoA acetyltransferase, mitochondrial ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
catalyzes the conversion of 2 acetyl-CoA molecules to acetoacetyl-CoA plus CoA [RGD, Feb 2006]
Uniprot Description
ACAT1: Plays a major role in ketone body metabolism. Defects in ACAT1 are a cause of 3-ketothiolase deficiency (3KTD); also known as alpha- methylacetoaceticaciduria. 3KTD is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded. Urinary excretion of 2-methyl-3- hydroxybutyric acid, 2-methylacetoacetic acid, triglylglycine, butanone is increased. It seems likely that the severity of this disease correlates better with the environmental or acquired factors than with the ACAT1 genotype. Belongs to the thiolase family.
Protein type: Carbohydrate Metabolism - butanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Amino Acid Metabolism - lysine degradation; Lipid Metabolism - fatty acid; Acetyltransferase; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.9; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis
Cellular Component: mitochondrial inner membrane; mitochondrial matrix; mitochondrion; peroxisome
Molecular Function: acetyl-CoA C-acetyltransferase activity; coenzyme binding; enzyme binding; metal ion binding; protein homodimerization activity
Biological Process: brain development; liver development; protein homooligomerization; response to hormone stimulus; response to organic cyclic substance; response to starvation
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Product Notes
The Rat Acat1 acat1 (Catalog #AAA2880903) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880903 ELISA Kit recognizes Rat Acat1. It is sometimes possible for the material contained within the vial of "Acetyl-CoA acetyltransferase, mitochondrial, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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